If you come across a beautiful woman with blue-purple lips, please do not easily think that she is a fashionable family or lipstick model, it is likely that behind the “glamour”, there is great pain, because the blue-purple lips are not artificial decoration, but the performance of a dangerous disease! Pulmonary hypertension, a chronic lethal disease, is considered the “cancer” of the cardiopulmonary vascular system. Due to the severe lack of oxygen in the lungs, the lips of patients often appear blue-purple, so they get a figurative name – “blue lips”. Briefly, pulmonary hypertension (blue lips) can be divided into arterial pulmonary hypertension (i.e., the first type of pulmonary hypertension, including idiopathic pulmonary hypertension) and non-arterial pulmonary hypertension, which is usually referred to as arterial pulmonary hypertension. The endothelial cells grow rapidly and extensively in the lumen of the pulmonary artery and block the pulmonary artery, increasing the pressure in the pulmonary artery and making it difficult to return blood from the veins. Without proper treatment, the patient may die of uncorrectable right heart failure.