The common reasons for weakness of hands and feet and weakness of body and panic are as follows: Firstly, before the application of drug treatment, diabetes patients have severely higher than normal blood sugar with impaired glucose metabolism, and the required energy supply is insufficient. Secondly, patients with liver cancer will suffer from serious physical depletion due to abnormal liver function and tumor metabolic syndrome, and patients will suffer from severe and serious malnutrition. Thirdly, patients with severe arrhythmia, such as ventricular tachycardia, will have decreased ejection function of the heart and insufficient blood and oxygen supply to the whole body. Fourth, patients with heart failure have edema in the abdominal extremities and other parts of the body due to stagnation of blood in the arterial and venous circulation, poor systemic blood circulation, and insufficient blood and oxygen supply. Fifth, patients with infections and fever in the intestinal tract and lungs due to inflammatory effects, resulting in severe energy consumption and malnutrition.