The redness and swelling of the place after vaccination is considered to be related to the adverse reaction of vaccine, drug stimulation, bacterial infection, etc., which can be relieved by strengthening the local care, wet compresses, medication, and so on. 1. Adverse vaccine reaction: the redness and swelling of the place after vaccination may be related to the adverse vaccine reaction, which will be relieved by itself after 2~3 days, and no special treatment is needed. 2. Drug stimulation: redness and swelling after vaccination may be caused by drug stimulation of the local reaction of the vaccination site, first of all, you can use skin disinfectant, local disinfection, cold compresses can be used to reduce the scope of redness and swelling within 24 hours, more than 24 hours can be used to dilate blood vessels through the hot compresses, to promote the dissipation of redness and swelling. 3. Bacterial infection: after the vaccine place red and swollen considered to be due to the wound water caused by bacterial infection, pay attention to local skin care, try to avoid water, to ensure that the local skin dry, promote the wound to recover as soon as possible, you can iodine local disinfection, to avoid local aggravation of the infection, but also comply with the doctor’s instructions for oral antibiotics, such as amoxicillin capsule, cefixime tablets and so on. If the redness and swelling of the place where the vaccine has been administered continues not to subside, it is recommended to go to the hospital in time, under the guidance of the doctor’s treatment, and not blindly self-medication, to avoid delaying the condition, resulting in other damages.