The life expectancy of mitral regurgitation depends on the degree of regurgitation and the availability of timely treatment. Mild regurgitation generally does not affect the life expectancy, while severe untreated regurgitation causes complications and can easily lead to death. 1. Mild mitral regurgitation: Mild regurgitation usually has no obvious symptoms and does not require special treatment if the left ventricular function is normal. It is recommended to follow up regularly, and pay attention to rest, avoid overwork, and keep a good attitude, which has no effect on natural life, and its survival period is the same as that of normal people. 2. Moderate mitral regurgitation: If symptoms such as chest tightness, palpitations, fatigue, edema, etc. occur, it is recommended to avoid excessive physical labor and follow the doctor’s prescription for the cause of the disease. Spironolactone and hydrochlorothiazide can be used to improve edema; metoprolol and captopril can be used to reduce the burden on the heart. Through active treatment, clinical symptoms can be relieved and complications can be prevented, thus effectively reducing the impact on life expectancy. 3. Severe mitral regurgitation: if not treated in time, this period will easily lead to heart failure, and may even lead to cardiogenic shock, and may lead to death if not rescued in time. However, if the treatment is reasonable, after correcting the regurgitation situation, the patient can survive for a long time. Surgical treatment such as valvuloplasty or mitral valve replacement is generally recommended for those who meet the indications for surgery. Anticoagulants such as warfarin should also be taken as prescribed after surgery. Mitral regurgitation is caused by mitral valve closure insufficiency, in which part of the blood in the left ventricle regurgitates through the mitral valve into the left atrium during cardiac systole due to abnormalities in the mitral valve apparatus or the left ventricle. It must be followed up regularly and treated promptly.