The technique of making wax block for pathological cytology of thoraco-abdominal fluid is to make a conventional wax block for cytology of thoraco-abdominal fluid sent for examination, through the processing of pathological technical process, to save its cellular components in the wax block, so that the section can be diagnosed under the conventional microscope, to discriminate the nature and type of cells, and to achieve a more accurate diagnosis of tumor cells. Method of production: After receiving the thoracic and ascitic fluid, it will be sedimented for 1 hour, then aspirate the bottom liquid into a plastic centrifuge tube, add 5ml of 10% formalin solution, centrifuge 3500/5min, pour off the supernatant, add 5ml of 10% formalin solution, centrifuge, repeat 1 time and leave it to stand, wait for the material to be taken, take the material and wrap it with filter paper, and go through dehydration -The process of dipping wax – embedding – sectioning – microscopic diagnosis – report issued, etc., to make disease diagnosis of thoracoabdominal fluid; Clinical significance : 1, increase the number of cell smear, density, and do a good preservation of cells, both to Repeat multiple slices, and assist tumor immunohistochemistry detection, which improves the positive rate of tumor diagnosis in thoracoabdominal fluid. 2. When tumor cells are detected, the cell types can be well typed, which provides more reference basis for tumor standardization treatment. 3. This technology is more accurate and more convenient to save than the previous ordinary smear of exfoliative cytology, which makes the diagnosis of disease more clear. Precautions: 1. When sending chest and abdominal fluid for examination, the container should be clean, as much as possible, and fresh. 2.When billing pathology for examination, use the pathology routine application form and fill in the relevant medical history carefully and bill the fee [abbreviation: pathology examination once]. In conclusion, this technology plays a very good effect on the diagnosis of tumor cytology of thoracoabdominal fluid, and has been recognized by the clinic and patients. At present, the department has been able to carry out this technology, and we hope to provide better services for the clinic and patients.