If the acute kidney injury causes the glomerular filtration rate to drop to 60ml/min, it is possible to cure it, but if it is caused by chronic kidney disease, it cannot be cured. 1. Acute kidney injury can be categorized into pre-renal, renal and post-renal according to its etiology. If pre-renal and post-renal acute kidney injury can be diagnosed and treated at an early stage, most of the renal function can be recovered. However, the prognosis of renal acute kidney injury is relatively poor, with high mortality rate, and some of the surviving patients will develop chronic kidney disease, or even lifelong replacement therapy. 2. Chronic kidney disease is divided into 5 stages, glomerular filtration rate of 60ml/min belongs to stage 2 of chronic kidney disease, which is regarded as early stage, but due to its irreversible and continuous progression of the disease, and there is no relevant specific drug, so the treatment is mainly to slow down the progression of renal function to end-stage renal disease (i.e., uremia), which requires renal replacement therapy and is incurable at the present time. Therefore, when abnormal renal function is detected, treatment should be carried out in regular hospitals in a timely manner. Early detection, early diagnosis, early treatment and regular review will have great benefits to the prognosis.