Some hypoglycemic drugs will appear to inhibit appetite, common drugs are biguanides, α-glucosidase inhibitors, GLP-1 receptor agonists and so on. 1. Metformin: Metformin inhibits hepatic gluconeogenesis, reduces intestinal absorption of glucose, and is prone to cause nausea, decreased appetite and other adverse reactions, such as metformin. 2. α-glucosidase inhibitors: inhibit the decomposition of carbohydrates, reduce the absorption of glucose in the intestinal tract, easy to cause decreased appetite, bloating and other adverse reactions, such as acarbose, voglibose and so on. 3. GLP-1 receptor agonists: these drugs have the effect of suppressing appetite and delaying gastric emptying, such as liraglutide. The mechanism of action of each drug, adverse reactions are not the same, need to be in the physician or pharmacist under the guidance of the combination of their own condition reasonable use, not unauthorized use of medication, the emergence of adverse reactions in a timely manner, so as not to delay the condition.