Pediatric dry cough at night can be seen in respiratory tract infections, cough variant asthma, etc., with what “anti-inflammatory drugs” or whether you need to use, according to the cause of the decision, such as Mycoplasma pneumoniae caused by respiratory tract infections, the need to use azithromycin therapy. 1. Respiratory tract infections: such as acute bronchitis and bronchopneumonia caused by Mycoplasma pneumoniae infection, clinical dry cough at night, some may be accompanied by fever, perfect Mycoplasma pneumoniae antibody test can help diagnosis. These children should be treated with macrolide antibacterial drugs, such as azithromycin or erythromycin to fight infection. 2. Cough variant asthma: the clinical recurrent cough, mostly dry cough, often at night, but also in the morning or after activity, lung function test suggests that the airway reactivity is increased. In these children, antimicrobial therapy is ineffective, so no “anti-inflammatory drugs” are needed. Fluticasone aerosol can be used for relief. There may be other causes of dry cough at night, and it is advisable to consult a doctor to determine the cause. Medications should be chosen by a specialist based on the child’s condition, and active medical attention is recommended.