White patches may be associated with albinism and are considered to be related to family history and genetic mutations. Vitiligo and non-pigmented nevi also manifest as white patches, and the cause is not yet fully understood. Treatment modalities include general treatment, medication, physical therapy, and surgery, which can help improve. 1. Albinism: patients with albinism in the family, albinos, genetic mutations, may induce albinism. Need to do a good job of sun protection, avoiding light, to avoid aggravation of symptoms. Currently the lack of a cure for the disease, need to take sun protection measures to avoid ultraviolet damage to the eyes and skin. 2. Vitiligo: vitiligo pathogenesis is not yet completely clear, consider with genetic mental neurological factors, autoimmune diseases. You can give hydrocortisone butyrate, pimecrolimus ointment topical coating, combined with 308 excimer laser helps the skin to restore color. Post-inflammatory depigmentation spots, stable vitiligo, can take transplantation treatment. 3. Aberrant nevus: Aberrant nevus, the cause of which is unknown, is considered to be related to melanin aggregation and transportation disorders, resulting in white patches on the skin, and if it is caused by an aberrant nevus, it usually does not require special treatment. In addition to this, there are other diseases that may cause white patches on the skin, and needle sex treatment is recommended. The specific treatment should be decided by combining the cause of the disease, the size of the plaque, the patient’s own condition, and the examination results.