Yellow eyes may be caused by physiological factors, but also may be caused by chronic conjunctivitis, conjunctival pigmented nevus, elevated bilirubin levels and other pathologic factors, it is recommended to consult a doctor in a timely manner, and can be treated by medication or surgical methods to treat the primary disease. 1. Physiological factors: prolonged close eye use, long time looking at cell phones, computers, etc., can easily lead to scleral hyperpigmentation, look yellowish eyeballs, this situation can be improved through the development of good eye habits, the use of eye drops, local massage and hot compresses to improve visual fatigue, so as to reduce the hyperpigmentation. 2. Pathologic factors: (1) chronic conjunctivitis: conjunctival tissue pigmentation caused by yellowing of the eyes, need to use antibiotic eye drops such as penicillin ophthalmic solution, chloramphenicol ophthalmic solution for treatment at regular intervals, conjunctivitis eliminated, the pigmentation will gradually subside. (2) Conjunctival nevus: yellowing of the eyeballs caused by the accumulation of pigment in the conjunctival tissue, which needs to be surgically removed in order to improve the appearance of yellowing of the patient’s eyeballs. (3) Viral hepatitis: Patients with viral hepatitis B or C often have impaired liver function, which can be manifested by yellowing of the eyes. Antiviral drugs, such as lamivudine and entecavir, should be used for treatment as prescribed by the doctor. If the yellow color of the eyes is found, if physiological factors are excluded, the patient needs to go to the hospital in time, to clarify the specific causes and standardized treatment.