HFMD lesions usually appear on the hands, feet, and mouth, but which area appears first varies from person to person. HFMD lesions usually appear on the hands, feet, and mouth, and can occur simultaneously, depending on which part of the body they appear on first. However, they can also be incomplete, such as occurring only in the mouth. The oral cavity is the most commonly affected area. The lesions of HFMD typically appear as early red blotches that develop into thin-walled, clear blisters surrounded by a red halo. When the blisters rupture, grayish-white vesicles or ulcers may form. If there is any discomfort, it is recommended to seek prompt medical attention and follow the doctor’s instructions.