Candidates of a year of age often ask: every day I can feel the aging of my facial skin myself, and more and more wrinkles, what can I treat to slow down the aging process? As we age, our skin gradually shows signs of aging. The process is divided into two main pathways, endogenous and exogenous. Endogenous aging is the result of genetic differences and years of deposition in each individual, and this process cannot be avoided, while exogenous aging is produced by external factors (smoking, alcoholism, malnutrition, sun exposure) and other problems, and this process can be avoided through personal care. Some data show that 80% of facial aging can be attributed to sun exposure, ultraviolet radiation, resulting in collagen fragmentation, denaturation, making the skin sagging, wrinkles; and smokers face aging and wrinkles than non-smokers to come more serious. But what should we do when the signs of age have already appeared on our face, and it is difficult to work through normal daily care? My answer is to use the power of medicine. Wrinkles are categorized into dynamic and static wrinkles. Wrinkles that appear during expression activities are called dynamic wrinkles, while wrinkles that can be seen without expression are called static wrinkles. Dynamic wrinkles can be treated with botulinum toxin. Botulinum toxin can not only accurately brakes the target expression muscles to make the dynamic wrinkles disappear, but also prevents the formation of static wrinkles. For static lines that have already formed, fillers can be injected at the initial stage to improve them. For the more serious static lines, often accompanied by skin laxity, tissue volume decline and other aging manifestations, this time simple cosmetic injections may not achieve the expected results, can be combined with the application of laser cosmetic treatment of some of the technology.