Waking up at 3 o’clock in the middle of the night and not being able to sleep may be due to kidney deficiency, but it is also necessary to diagnose and treat according to the patient’s condition, and it is common that the heart is overflowing with fire, phlegm fire disturbs the heart, and kidney deficiency and other evidence. 1. Excessive fire in the heart: manifested as upset and insomnia (hot and bothered in the heart, insomnia symptoms), anxiety (heartbeat, panic), short and red urine (small amount of urine, dark yellow color), restlessness, mouth and tongue sores, dry mouth, red tongue, moss, thin yellow, and so on. 2. Phlegm fire disturbing the heart: manifesting as insomnia, belching (hiccups), generalized malaise, chest tightness and heartburn, etc., accompanied by bitter taste in the mouth, heaviness in the head and dizziness, red tongue with yellowish coating, and slippery pulse. 3. Kidney deficiency: in traditional Chinese medicine is divided into kidney yang deficiency and kidney yin deficiency, kidney yang deficiency is manifested as lumbar and knee soreness (lumbar and knee soreness and weakness) cold pain, limb warmth, fear of cold, mental depression, male impotence and premature ejaculation, women’s uterine cold infertility and other symptoms. Kidney Yin deficiency is manifested by symptoms such as Wuxingxiahe (heat in the heart of the two hands and the heart of the two feet, and self-consciousness of heat in the heart and chest), night sweating (abnormal sweating after going to sleep, and sweating stops after waking up), emaciation, soreness of the waist and knees, dizziness, tinnitus, and insomnia and dreaminess. If the patient’s symptoms are severe, or if they persist and do not improve, he or she should go to the hospital for treatment.