Rickettsial infections are mainly treated with antibiotics of the corresponding type, either tetracycline or doxycycline of the tetracycline class, or sometimes azithromycin or fluoroquinolones of the macrolide class. Rickettsia infections are louse-borne typhus caused by Rickettsia przewalskii and murine typhus caused by Rickettsia mosquito, but these two are seen less frequently at present, because human lice as well as fleas parasitizing on humans are difficult to see with better sanitation. In contrast, the Orientals of scrub typhus are mainly transmitted to people through the bite of scrub mites, so they can still be seen clinically. When applying the drug, the amount of doxycycline is high, and the first dose can be doubled, and after applying the drug for a period of time when the body temperature drops to normal, it is best to apply it again for 7-10 days to prevent rekindling.