Thyroid peroxidase autoantibodies of 66IU/ml are on the high side, while other indicators are normal, no special intervention is needed at present, and regular review is sufficient. Normal thyroid peroxidase autoantibodies are generally 0-34IU/ml, and the reference ranges may vary from laboratory to laboratory. 66IU/ml is generally mildly high, and other indicators are normal, which may suggest the presence of Hashimoto’s thyroiditis, which does not require much intervention, and can be checked with regular blood tests for thyroid function, neck ultrasound, and so on. Hashimoto’s thyroiditis is a type of autoimmune thyroiditis, and abnormalities in thyroid peroxidase autoantibodies and thyroglobulin antibodies are the main causative factors of Hashimoto’s thyroiditis. The presence of abnormal thyroid function, accompanied by a marked increase in thyroid peroxidase autoantibodies during regular checkups, may indicate the progression of Hashimoto’s thyroiditis, and standardized treatment should be carried out under the guidance of the clinician.