Severe premature beats can be treated overall with medication, surgery, and lifestyle interventions. Usually, if there is no organic heart disease in severe premature beats, frequent premature beats can be treated with certain oral medications, such as beta-blockers, non-dihydropyridine calcium antagonists, to carry out anti-arrhythmic treatment. If the patient has organic heart disease, such as coronary artery disease or myocarditis, medication should be applied to treat the primary heart disease; severe premature beats can also be treated by surgery, such as catheter ablation is a way to treat premature beats. After catheter ablation, patients should continue to take certain oral medications to maintain premature beats, such as amiodarone and beta-blockers.