Drugs in the azole class refer to proton pump inhibitors, and common drugs include omeprazole and lansoprazole. The common drugs of proton pump inhibitors (PPI) can be broadly categorized into the first generation PPI (represented by the drug omeprazole), the second generation PPI (represented by the drug lansoprazole), and the third generation PPI (represented by the drugs pantoprazole, rabeprazole, esomeprazole, and epprazole) according to the sequence of their development time. These drugs are commonly used to inhibit gastric acid secretion and are suitable for the treatment of peptic ulcer, gastroesophageal reflux disease (GERD), Drexel-Ayer syndrome, etc. They can also be used in combination with antibiotics (e.g., amoxicillin, clarithromycin) and bismuth (e.g., flucytoside) to treat Helicobacter pylori infections. It should be noted that proton pump inhibitors are contraindicated in people who are allergic to them or in people with severe renal impairment, etc. Adverse reactions such as nausea and diarrhea may also occur during the process of using the drug. It should also be noted that the dosage and therapeutic effect of different proton pump inhibitors may vary from one individual to another. Therefore, the use of such drugs should be under the guidance of a doctor, according to the actual situation of the individual drug selection and standardized use, do not blindly use drugs or increase or decrease the amount of drugs, so as not to cause adverse consequences.