High transaminases due to muscle strain usually come down on their own by resting the transaminases. Muscle cells usually contain high levels of aminotransferases, and when a muscle is strained, the damage to the muscle cells will cause the aminotransferases to be released into the bloodstream, resulting in high aminotransferase levels in the blood test. However, this high level of aminotransferase does not last long, and it usually comes down gradually after stopping exercise and resting. After a muscle strain, the strained area should be avoided to prevent the injured muscle from being pulled, causing swelling and pain, which will affect the recovery of the muscle strain and the decrease of transaminases. The high aminotransferases caused by muscle strains need to be checked regularly. If the aminotransferases continue to rise but do not fall, it is recommended to go to the hospital as soon as possible and take appropriate measures under the guidance of the doctor.