In reality, many of our friends are troubled by major or minor diseases. Cranial defects are one of these diseases. Craniosynostosis is a partial loss of the skull and loss of the original shape of the head. This not only causes fear and insecurity because of the lack of a normal skull shape, but also affects the health of the patient. The cause of craniosynostosis is usually caused by traumatic brain injury, but there are also other causes, such as severe infections that lead to bone necrosis, or congenital bony deformities. In this case, it is necessary to repair the skull. The dangers of cranial defects Cranial defects can cause a large number of sequelae, which are related to the degree of injury, and the symptoms vary from person to person. In less severe cases, the symptoms may include headache, anxiety, depression, dizziness, panic, chest tightness, loss of appetite, sleep disturbance or neurological disorders. Those with severe injuries have more sequelae, such as paralysis of limb functions, incontinence, memory impairment, dementia, etc. Cranial repair materials: Most of the cranial repair materials used clinically are titanium mesh materials and peek polyetheretherketone materials. Peek material is suitable as the choice of cranial bone repair material. Peek material has better performance compared to other materials, and the advantage of the material compared to titanium mesh is that it is more histocompatible. It is more comfortable and thicker. It is similar to human skull. Especially for pediatric patients, it can better adapt to the growth and development of human autogenous cranial bone. And it will have a lower rate of infection and rejection. The important point is that polyetheretherketone material is a material that can be plasticized in three dimensions, it can be customized in three dimensions according to different patients’ conditions and really restore the physiological structure of the skull perfectly. Cranial repair surgery process 1, the first need for three-dimensional CT scan of the patient’s skull to extract accurate three-dimensional data, three-dimensional reconstruction, 3D printing to produce a personalized PEEK repair material that perfectly fits the structure of the bone window. 2.The scalp is incised during the surgery, and the layers of tissue are carefully separated to expose the bone window, and then the material is precisely affixed to the bone window and adjusted and reset. 3, well fixed with special lap screws, suture all layers of skin, and the surgery is complete. 4.After the operation, pay attention to give antibiotics to prevent infection, hemostasis and neurotrophic drug treatment; pay attention to observe the changes of the patient’s surgical cavity drainage, change medication regularly and observe the healing of the incision.