Irbesartan hydrochlorothiazide belongs to the compound preparation, the drug can be broken to take, and does not affect the effectiveness of the drug. Amlodipine benzenesulfonate is a calcium antagonist, belongs to the long-acting preparation, can also be broken to take. However, whether you can take one and a half should refer to the specific dose, to choose the appropriate dose under the guidance of the physician. 1. Irbesartan hydrochlorothiazide tablets is a composite preparation, Irbesartan is an ARB antihypertensive drug, hydrochlorothiazide is a diuretic antihypertensive drug, the combination of the two drugs has a synergistic effect on lowering blood pressure, and also reduces each other’s adverse reactions. Amlodipine benzenesulfonate is a calcium antagonist antihypertensive drug. 2. The adverse reactions of Irbesartan Hydrochlorothiazide include dizziness, fatigue, thirst, flu-like symptoms, nausea, abdominal discomfort, etc. It is forbidden to use for women who are allergic to the ingredients of the drug, have severe renal insufficiency, or are lactating during pregnancy. The adverse reactions of amlodipine benzenesulfonate include dry stools, lower limb edema, tachycardia, flushing, etc. It is forbidden for patients who are allergic to the ingredients of the drug. 3. When the two are used together for the treatment of hypertension, it is necessary to choose the appropriate dose under the guidance of the physician, one and a half tablets does not make clear the dose of the drug, and it is not possible to overdose the drug, it is necessary to choose the dose of the drug under the guidance of the physician with reference to the patient’s blood pressure level. If there is any discomfort, consult a doctor in time and follow the doctor’s instructions for medication.