The difference between Calcipotriol and Calcipotriol mainly lies in the types of drugs, indications, contraindications, adverse reactions, etc., the specific use of drugs should follow the doctor’s instructions. 1. Types of drugs: Calcipotriol is commonly used in the preparation of calcipotriol betamethasone ointment; Calcipotriol is commonly used in the preparation of calcipotriol ointment, calcipotriol application, and so on. 2. Indications: Calcipotriol is suitable for the local treatment of stable plaque psoriasis; Calcipotriol is suitable for the local treatment of common psoriasis (plaque, dribble, map and other forms). 3. Contraindications: Calcipotriol is contraindicated in those who are allergic to the drug and those with calcium metabolism disorder. Calcipotriol is not only prohibited for those who are allergic to it and those with calcium metabolism disorder, but also prohibited for those with severe hepatic/renal insufficiency, and other types of psoriasis such as punctate/erythrodermic/pustular, etc. It is also prohibited for those who have skin infections and ulcers when it contains betamethasone component. 4. Adverse reactions: Calcipotriol medication to local skin irritation (such as itching, burning sensation) of the most common adverse reactions, rare contact dermatitis, psoriasis worsening, hypercalcemia and hypercalciuria is rare. Calcipotriol, in addition to the above adverse reactions, can also be seen by betamethasone component of the skin atrophy, capillary dilatation and other symptoms. To sum up, those who have the need to use Calcipotriol or Calcipotriol should choose and standardize the use of the drug under the guidance of a doctor, and should not blindly use or increase or decrease the dosage of the drug on their own, so as not to cause adverse consequences.