Toe pain need to consider more factors, including the following: 1, trauma: trauma can easily lead to fracture and soft tissue damage, resulting in pain; 2, gout: this situation needs to be considered whether there is a large amount of alcohol or seafood consumption, it is recommended to go to the hospital to improve the blood uric acid and other checks; 3, nail groove inflammation, diabetic peripheral vascular disease or diabetic foot, can cause localized pain in the toes; 4, a history of arteriosclerosis of the lower limbs, severe gangrene can occur, thus causing pain in the toes. Occlusive disease history, serious cases can appear gangrene, thus causing toe pain. Therefore, there are more reasons for toe pain, need to be analyzed in specific cases, and it is recommended that patients go to the hospital for formal diagnosis and treatment.