Cough aggravated by sleeping at night may be related to increased vagus nerve excitability at night, or to respiratory diseases such as allergic rhinitis and cough variant asthma. 1. Vagus nerve excitation: at night the body’s vagus nerve excitability increases, leading to bronchial smooth muscle contraction, narrowing the bronchial lumen, coupled with increased respiratory secretion stimulation will lead to cough aggravation. 2. Allergic rhinitis: some people at night will also increase nasal secretions, postnasal drip and other stimulation of the throat, resulting in cough aggravation. 3. Cough variant asthma: due to airway hyperresponsiveness, especially at night or in the early hours of the morning, there will be airway spasm, mucus hypersecretion, increased secretion after the cilia swing, causing cough aggravation. There are many other causes of nighttime cough or aggravation, if you sleep at night with frequent coughing, you should go to the hospital in a timely manner, after a clear diagnosis by the doctor to arrange a scientific treatment program, not to be taken lightly or on their own, so as not to delay the condition.