Swelling and pain in the wrist of both hands, the possible causes are acute wrist injury, wrist strain, wrist arthritis, cervical spondylosis and so on. 1. Acute wrist injury: It may be caused by strains and contusions in sports, which may cause injury to the wrist joints, resulting in soreness, swelling and weakness. 2. Wrist joint strain: it may be due to long time use of the wrist joint, such as typists, embroidery, knitting and other people, which may cause aseptic inflammation of the joints, resulting in swelling, pain and weakness of the wrists. 3. Wrist arthritis: If patients suffer from gouty arthritis, rheumatoid arthritis, rheumatoid arthritis, etc., corresponding symptoms of wrist swelling, pain and weakness may occur. 4. Cervical spondylosis: the typical symptoms of cervical spondylosis are pain and numbness in the upper limbs and weakness in the hands, which may also lead to weakness, pain and swelling in the wrist joints of both hands. Swelling pain and weakness of both hands and wrists may also have other causes, it is recommended to go to the regular hospital in time to improve the relevant examination, clear the cause of the disease, under the guidance of the doctor to carry out targeted treatment or treatment.