Problems related to nebulizer inhalation therapy

With the arrival of winter, the weather is cold and haze is coming, children’s respiratory diseases show an explosive onset, such as upper sensation, bronchitis, pneumonia, etc. Then, in addition to the general application of oral medication or intravenous medication, another means of treatment that cannot be ignored is nebulizer inhalation therapy, which is effective for certain diseases such as wheezing diseases (capillary bronchitis, wheezing bronchitis, childhood asthma However, there is a lot of talk on the internet that nebulized inhalation therapy is more harmful than other treatments, but is it true? First of all, we need to be clear about what is nebulized inhalation therapy, secondly which drugs can be used for nebulized inhalation therapy and how safe they are, and then what are the ways of nebulized inhalation and which of them are more effective; we should also understand the risks and precautions of nebulized inhalation. What is nebulized inhalation? Nebulized inhalation is the use of high-speed oxygen-containing airflow to form a mist of medication, which is then inhaled through the respiratory tract to achieve the purpose of treatment. Nebulization is to make the drug into small droplets or particles of a few microns in diameter, also known as aerosols, and with breathing, the drug will directly enter the respiratory tract and lungs and be deposited in the alveoli, which is often used to relieve and treat asthma, cough and other respiratory diseases. There are several common types of nebulized drugs on the market, first, glucocorticoids, such as budesonide suspension, ryanocort, co-corticosterone, etc., of which budesonide suspension is more commonly used in clinical treatment and is currently the only inhaled glucocorticoid; second, bronchodilators, such as salbutamol, polycamcinolone, compound ipratropium bromide, etc., to relieve airway spasm; third, phlegm expectorants, such as acetyl Cysteine, etc. Currently, there is no nebulized inhalation usage in the oral or injection instructions of Ambroxol on the market, and it is controversial whether it is used for nebulized inhalation treatment. Virus replication; V. Humidification of the airway, saline, sterilized water for injection, etc., this is probably similar to the role of humidifiers. From the drug classification, we can clearly understand which drugs can be used for nebulization therapy, what role of the airway in the process of disease treatment, there will still be a lot of doubts, such as is my child suitable for nebulization, inhaled glucocorticoids side effects are obvious, what are the precautions in the nebulization process? Can antibiotics be used for nebulizer treatment? Let’s take a closer look here. Nebulizer inhalation is aimed at children of a wide age range, after birth, that is, in the neonatal period, if necessary, you can choose the appropriate medication and nebulization method for nebulizer treatment, especially for the recovery period of consolidation treatment phase, you can take home nebulization method, reducing the risk of going out and cross-infection in the hospital; at the same time, the safety of nebulizer inhalation is still relatively high, as long as you pay attention to some of the nebulizer inhalation As long as you pay attention to some precautions of nebulizer inhalation, the risk is still very small. Are inhaled glucocorticosteroids safe and do they have significant side effects? This may be the reason why a considerable number of parents are worried about or resistant to hormone nebulizer treatment. Before answering this question, let’s take a look at the authoritative statements about inhaled glucocorticosteroids. The 2008 Chinese guidelines for the diagnosis and treatment of bronchial asthma in children clearly state that inhaled glucocorticosteroids are emphasized as the first-line medication for acute asthma attacks and long-term asthma control. TheGlobalStrategyfortheDiagnosisandManagmentofAsthmainchildren5yearsandYounger) states that inhalation therapy is the cornerstone of asthma treatment for children aged 5 years and younger, and that inhaled glucocorticosteroids are preferred for the initial treatment of wheeze control in children under 5 years of age. What does this mean? It means that inhaled glucocorticosteroids are the first choice for nebulized treatment of wheezing episodes, regardless of the etiology, and of course, in the case of co-infection, anti-infection treatment is equally important. Some patients even need long-term nebulized inhalation therapy to prevent wheezing episodes. So do inhaled glucocorticoids have side effects, no doubt, but are they obvious? Not really. There are various side effects of hormones, such as osteoporosis, obesity due to metabolic abnormalities, hair growth, hyperglycemia, etc. But these often refer to the side effects after long-term application of large doses of hormones (oral or intravenous), while inhaled glucocorticosteroids have side effects, but they are relatively mild. Why? As long as we pay attention to cleaning the mouth and facial skin before and after nebulization, these adverse reactions can often be avoided when the child’s immune level is normal, and the systemic side effects of this treatment are mild and generally tolerable. Similarly, allergic cough and cough variant asthma, which are similar to the pathogenesis of wheezing diseases in children, can also be treated with inhaled glucocorticoids. In the flu epidemic season, such as winter and spring, we can choose to add interferon nebulization under the premise of relevant symptoms, which has a certain antiviral effect and is conducive to shortening the course of the disease and early healing. So, are all drugs available for nebulized inhalation? The answer should be no, just like many places at present various antibiotic enemas, hormone enemas and other therapeutic means, are beyond the instructions practical, for nebulized inhalation, some doctors will choose to be nebulized practical, including some Chinese medicine nebulization, I personally think that should be cautious, may be some ingredients but will aggravate the airway inflammatory response is not conducive to disease recovery, and may even lead to some serious consequences. So what are the precautions in the nebulization process? Generally, you should avoid nebulization just after eating, it is recommended that 1-2 hours after eating in a quiet state to avoid food reflux accidental inhalation when crying; clean the mouth before and after nebulization, nebulization area facial skin; try to choose sitting or semi-sitting nebulization, nebulization handle as vertical as possible to ensure that the drug can be effectively inhaled. At the same time, the choice of nebulization machine is equally important to ensure that the nebulized particles in the size of 1-5μm, too large can not be effective lung deposition, not play a good therapeutic effect, resulting in delay or aggravation of the disease, should try to choose medical nebulizer, and under the guidance of doctors for nebulization treatment, effectively ensure the safety of the child. In short, nebulizer inhalation treatment for respiratory diseases has a very good therapeutic effect, and high safety, is the main or important auxiliary treatment means, parents of children, according to the child’s condition, under the guidance of the doctor to carry out effective nebulizer inhalation treatment, is very helpful to the recovery of the disease.