The buttock injection referred to here refers to the intramuscular injection of the buttocks, and the site of the injection is chosen to avoid the sciatic nerve. When injecting drugs, except for a slight painful discomfort when the puncture needle enters the skin, the pain during the whole injection process is not severe and usually people can bear it. Except in the use of certain drugs may cause more obvious pain, common drugs are long-acting penicillin benzathine penicillin, in the use of this drug, some patients may appear obvious pain discomfort, and even some patients need to use a small amount of local anesthetic drugs before injection, and then drug injection, which can well relieve patients of pain discomfort. There is also the possibility that the operator may not operate properly at the injection site and touch the sciatic nerve next to it may also cause more severe pain and discomfort. However, for adults, intramuscular injection of the buttocks is not too obvious pain and can be tolerated.