Herpes zoster neuralgia includes neuralgia during the rash and postherpetic neuralgia, which can be relieved by medication and physical methods. Neuralgia during the rash can be symptomatically treated with antiviral, nutritive, and analgesic drugs, commonly used drugs include acyclovir, vasiclovir, methylcobalamin, and non-steroidal anti-inflammatory drugs such as diclofenac sodium. Neuralgia remaining after the rash subsides can be relieved by topical lidocaine patches; oral pregabalin, gabapentin and other calcium channel modulators. Neurointerventional techniques such as nerve block, selective nerve destruction, etc., neuromodulation techniques such as pulsed radiofrequency therapy, electrical nerve stimulation, etc., ultraviolet, infrared or ultrashort-wave irradiation, etc., can also alleviate postherpetic neuralgia. All drugs should be used under the guidance of medical professionals to avoid adverse reactions.