Cholangiocarcinoma is a malignant tumor of the extrahepatic bile duct originating from the confluence of the right and left hepatic ducts to the lower end of the common bile duct. The occurrence of cholangiocarcinoma is closely related to lifestyle. In recent years, the significant increase of people’s poor lifestyle has led to the trend of increasing the incidence of cholangiocarcinoma and other cancers year by year. With the intensification of social competition, people’s work and life stress increase and their body and mind are in a subhealthy state for a long time, which leads to neurological regulation and metabolic disorders. People’s diet structure gradually changes from coarse grains and vegetables to large fish, meat, high-fat and high-calorie diet, and drinking a lot of alcohol, too much strong coffee and drinks containing preservatives have also become part of many people’s diet structure. In addition, people use cars to walk more, physical activity is significantly reduced, and many people are in the state of sitting and moving less. These can cause poor bile excretion and a lot of stagnation in the gallbladder and bile duct, if the body is accompanied by obesity, it will further increase the cholesterol content in the blood, aggravating the impact on the function of the bile duct. This, over time, may lead to gallstones, chronic inflammation of the biliary system, and even cancer.