The cost of early Down’s syndrome screening is between$300-400, which may vary slightly from hospital to hospital. Early Down’s syndrome screening is done between 11-14 weeks of pregnancy by taking the blood of the pregnant woman. The risk of the fetus suffering from Down syndrome is mainly determined by testing the levels of alpha-fetoprotein, human chorionic gonadotropin and free estriol in the blood of the woman, and then considering the risk of trisomy 18 and trisomy 21 in combination with the week of pregnancy and age, etc. If there is a positive result, a DNA test or amniocentesis is required for a clear diagnosis. The birth of a child with Down’s syndrome can seriously affect intelligence and quality of life, but it can be detected during pregnancy to reduce the birth of such children and improve the quality of the baby.