Enlarged submandibular gland should be treated according to the cause. Common causes include obstructive submandibular gland inflammation, submandibular gland tumor and so on. Commonly used treatments include medication and surgery. Obstructive submandibular gland inflammation: there is no effective treatment drug, the commonly used drugs in the acute stage are antibiotics such as amoxicillin, cefotaxime sodium, etc. If the condition is serious, the function of the gland will be lost. If the condition is serious and the function of the gland is lost, surgical treatment such as submandibular gland resection can be performed. Tumor of submandibular gland: the efficacy of chemotherapeutic drugs on the tumor is not accurate, the treatment method is mainly surgical resection, the principle is to remove the tumor and the whole gland, if the tumor is malignant, it is necessary to expand the scope of resection. If the resection range of the tumor is sufficient, the tumor lesion is limited generally do not need further radiation therapy. There may be other reasons for the enlargement of submandibular gland, you should go to the hospital in time, improve the examination to clarify the cause of the disease and then give targeted treatment. The above drugs should be used under the guidance of a doctor.