There are several possibilities for anal itching while sleeping: 1. Due to the presence of parasitic worms inside the intestinal tract, its most typical feature is to make the patient feel itchy at night. The most typical symptom is itching, and the more itchy you are, the more you want to scratch, and it is not easy to cure. The most typical symptom is itchiness, the more you want to scratch, not easy to cure, once you eat irritating food or anal damp heat will recur. The reason for this is that it is very complicated to sleep with an itchy anus, so it is advisable to go to the anus department of the hospital to have a checkup to clarify the cause and then prescribe the right medicine.