Insomnia after chemotherapy may be due to the fact that the patient is more nervous, or the use of glucocorticoids may cause the patient to become excited. For both cases, it is usually necessary to communicate with the patient before chemotherapy to inform him of the possible discomfort or adverse reactions after chemotherapy. If sleeplessness is a problem, sedative drugs may be appropriate. In the chemotherapy can use olanzapine, on the one hand, has the effect of antiemetic, but also can have a sedative effect, after the use of the patient’s sleep quality will be significantly improved, nausea, vomiting can also be improved. Try to keep the surrounding environment as quiet as possible during chemotherapy, and educate the patient’s family members. Because often the family’s uneasiness or anxiety, will also affect the patient’s sleep. If you can let the patient have a more comfortable or quiet environment, it will be very good for sleep after chemotherapy.