Gastroscopic biopsy of two small pieces alone does not indicate the severity of the disease, and the severity of the disease should be analyzed after the return of the pathology report. In the process of gastroscopy, if there are mucosal bulges, ulcers, or whitish mucosa suspected to be atrophic gastritis, etc., it is necessary to take biopsies of the lesions for pathological examination, generally according to the specific circumstances of the biopsy of one or more pieces, but the severity of the disease can not be judged by the number of pieces taken. Pathological examination is the gold standard for diagnosis of disease, if the pathological results consider polyps, ulcers, etc., it generally suggests that the lesion is not serious; but if the pathological results suggest that it is a malignant tumor, it generally suggests that the condition is serious, and it should be promptly consulted for medical treatment.