HBV is Hepatitis B virus and DNA is the viral load, HBV-DNA1.262E+05 means that you have been infected with Hepatitis B virus and the virus is replicating in your body, which means that your condition is more serious. The normal value of HBV-DNA is less than 1,000copis/mL, and the current HBV-DNA1.262E+05 indicates that the DNA of the hepatitis B virus has reached about 126,000copis/mL, which is a manifestation of a high viral load, indicating that the hepatitis B virus is active in the body at the moment, and it may be in a state of replication, and the test result is more serious. If the current HBV-DNA1.262E+05, without timely antiviral treatment, the virus will keep invading the liver tissues, and in serious cases, it will affect the liver cells, resulting in necrosis of the liver cells, and the liver function will not be able to operate normally, so the condition is more serious. If HBV-DNA viral load is found to be high and replicating, oral antiviral drugs such as entecavir should be taken as soon as possible according to the doctor’s prescription, and interferon injection should be given under the doctor’s guidance if necessary. After that, you should go to the hospital regularly for quantitative testing of HBV-DNA and other related examinations.