Insect bite dermatitis is a condition that occurs when the patient’s skin becomes visibly swollen, painful, or itchy after being bitten by something. This is a condition of skin irritation caused by mosquitoes or other insect bites. Patients can first apply glucocorticosteroid ointment, as well as glyburide lotion for topical application. The majority of patients can quickly control the condition with the application of these topical medications, but if some patients are bitten more often and the symptoms are more obvious and serious, they can also be combined with oral antihistamines, such as loratadine, cetirizine, these drugs can be applied. However, if the local itching is serious and there are obvious skin breakouts and oozing, the application of stove glycolic lotion is not recommended. Patients can apply boric acid solution for local wet compresses, along with glucocorticoid ointment for external application.