Nowadays, it is commonly used to kill H. pylori is a quadruple therapy containing bismuth, the course of treatment is 10-14 days, generally recommended to 14 days, the specific medication is an acid suppressant, a bismuth, plus two antibiotics. Acid suppressants commonly used are rabeprazole, omeprazole, estramiprazole, etc. Bismuth agents generally used are bismuth potassium citrate, colloidal bismuth. Antibiotics are amoxicillin, clarithromycin, metronidazole, levofloxacin, furazolidone, tetracycline, etc. These antibiotics in relative amoxicillin, furazolidone, tetracycline bactericidal effect is the best, but furazolidone and tetracycline are two old drugs, side effects are relatively large, if there is no penicillin allergy, the preferred application of amoxicillin. In addition, it can be combined with clarithromycin and metronidazole. Levofloxacin is usually placed inside the remedial program and used. You can say a specific program: rabeprazole 20mg, half an hour before meals in the morning and evening; bismuth potassium citrate 0.6mg, half an hour before meals in the morning and evening; amoxicillin 1.0mg, half an hour after meals in the morning and evening; clarithromycin 0.5mg, half an hour after meals in the morning and evening, two weeks of medication, after a month of discontinuation you can review the breath test to see if H. pylori has been killed.