Subcutaneous soft tissue tuberculosis infection requires anti-tuberculosis treatment, and more serious skin lesions require surgical treatment. Subcutaneous soft tissue tuberculosis infection is mainly due to the skin was infected by Mycobacterium tuberculosis, caused by the subcutaneous tissue lesions, mainly manifested in the skin lumps, ulcers, prone to the formation of skin abscess, abscess rupture, the formation of sinus tracts and other symptoms. This kind of skin tuberculosis disease emphasizes the use of 3~4 kinds of anti-tuberculosis drugs at an early stage in sufficient quantity, regularity, and throughout the treatment mainly for the purpose of delaying and preventing the drug resistance of Mycobacterium tuberculosis. If it is a smaller skin lesion, it can be treated without surgery. If it is a wart-like skin tuberculosis, it needs to be surgically removed at an early stage, but most of them will leave scars. It is recommended to go to the appropriate department of the hospital in time, timely treatment, good disinfection and isolation, and instruct the family to closely observe the patient, tuberculosis is contagious, if the skin tuberculosis and tuberculosis coexist, the patient needs to pay attention to the treatment of their own sputum.