HPV is a small DNA virus. HPV genome is a closed-loop double-stranded DNA, -HPV infects humans through direct or indirect contact with contaminated objects or sexual transmission, the virus only stays in the skin and mucous membrane after infection, -Common warts, commonly known as wart: mainly 1, 2, 4 The main types of warts are 2 and 4, which are found on the calloused surface and cause pain when walking – Flat warts are 3 and 10, which are found on the face, hands, arms and knees. Genital warts are the most common and have an important role in sexually transmitted diseases – HPV associated with cervical cancer: 16 and 18.