Pneumococcal 23-valent is mainly used for people with high risk factors for infection and is not recommended for non-immunodeficient people. The 23-valent pneumonia vaccine protects against 23 types of pneumococcus and is a “polysaccharide” vaccine. It is a “polysaccharide” vaccine and is not effective in protecting younger children, especially infants and children under 2 years of age. Therefore, the vaccine is intended for people over 2 years of age who are at high risk for pneumococcal disease, and usually only one dose is needed. People with risk factors for infection can be revaccinated more than 5 years after vaccination. The active ingredient of the 23-valent vaccine is derived from pneumococcal podocarp polysaccharide, and the response type of the polysaccharide vaccine is humoral immunity. The polysaccharide is a non-T-cell-dependent antigen (semi-antigen) that does not generate immune memory and has a short duration of immunity. Therefore, vaccination is not recommended for non-immunodeficient people. Vaccination should be given to healthy elderly people over 65 years of age, nephrotic syndrome, chronic organ failure, immunocompromised people and people with functional or anatomical absence of spleen. If you are unable to make your own decision, it is recommended that you seek medical advice and consult your doctor for professional guidance.