The causes of high HDL cholesterol include: a. Diet, eating too much fatty food, such as fish, chicken, shrimp, pork, etc.; b. In addition to diet, there are lifestyle factors that can lead to elevated HDL cholesterol levels, such as low exercise, high body weight, high body mass index; c. This index may also be elevated because of long-term smoking, resulting in elevated serum There are also some diseases that may increase this level, such as diabetes, and patients with type 2 diabetes may have elevated HDL cholesterol because of insulin resistance; V. There are some drugs that may increase this level in the serum.