Acute hepatitis B is curable, that is, it can be completely cured, but chronic hepatitis B currently has no specific drugs to completely cure. Although the nucleoside antiviral drugs and interferons currently used have clear antiviral efficacy, they control the replication of the virus and delay the progression of the disease, but cannot completely remove the hepatitis B virus from the body. To completely eradicate the hepatitis B virus, a good immune response is needed to achieve the effect.