Herpes zoster is an acute infectious skin disease caused by the varicella zoster virus, commonly known as “snake sores”, “tangled waist fire sores”, “spider sores” and “fire sores”. It is commonly referred to as “snake sores”, “tangle sores”, “spider sores” and “fire sores. With regular treatment, herpes zoster can usually be cured in about 2 weeks. However, when the herpes is cured, severe pains continue to occur, such as “burning, electric shock, and pins and needles”, making the patient suffer. If this pain is not properly treated in the early stages, it can develop into “postherpetic neuralgia”, which is the most common complication of shingles. It is common to have persistent pain for more than three months after the herpes zoster lesions have subsided, due to viral invasion of the local skin, usually in elderly patients, and the pain is unbearable. 25%-50% of middle-aged and elderly patients have post-herpetic neuralgia that lasts for decades, causing great pain to patients and their families. What can be done to treat post-herpetic neuralgia? Currently, the clinical treatment measures for postherpetic neuralgia are complicated, and the efficacy varies. Oral drugs include various painkillers, antidepressants and anticonvulsants; topical drugs include lidocaine patches, capsaicin ointment, buprenorphine patches and so on. Secondly, physical therapy, local ultra-laser irradiation and low-frequency electrical stimulation are more commonly used. The third is nerve block therapy, according to the location of pain for the corresponding area of nerve block to block the nerve conduction of pain, such as supraorbital and infraorbital nerve block, lumbar and thoracic paravertebral nerve block, continuous epidural block, etc., currently used more, and achieved better results. The purpose is to block local nerve conduction or inhibit pain conduction through the central nervous system. The main treatments include intercostal or paravertebral nerve radiofrequency destruction, spinal cord electrical stimulation, subarachnoid micro-pump continuous drug delivery, etc. Although this disease is currently a medical problem, but as long as the early onset of pain to the regular hospital pain department in a timely manner, through the above-mentioned treatment, I believe that the patient’s pain can be significantly reduced or cured, so that this “immortal disease” can be effectively controlled, bringing good news to patients.