There is generally no significant difference in symptoms between duodenal ulcers infected with H. pylori and those not infected with the bacterium, but it is possible to examine them with a breath test, etc. Aggressive treatment of H. pylori is conducive to the recovery of ulcers. Helicobacter pylori is only one of the causative factors, regardless of whether or not it is infected with this bacterium, duodenal ulcers may be manifested as regular abdominal pain, that is, the abdominal pain is significant on an empty stomach and is relieved after eating a meal. Studies have shown that there is a significant correlation between a large percentage of peptic ulcers and H. pylori infection. However, there will also be patients with H. pylori-negative ulcers, which suggests the presence of other causative factors. Patients can determine if they are infected with H. pylori by using a C14 or C13 breath test. If infection exists, aggressive treatment can prevent further irritation and damage to the duodenal mucosa and facilitate remission. Patients with duodenal ulcer, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor to carry out standardized treatment, to clarify the cause of the disease, and promote the rapid alleviation of the condition.