Children may have granulation when their wheals heal. Localized granulation tissue may appear after an erysipelas heals, which is a localized abscess caused by the erysipelas itself breaking down. Because the pus in the pus cavity has not been completely drained at the time of rupture, localized granulation tissue can appear, which can occur when a child’s wheals heal. If the granulation tissue protrudes, or is localized to a distinct palpation, a hard knot or lump can be touched with the hand. The first step is to perform surgery on the area where the wheal has broken down, and then remove all of the granulation tissue that has been produced in order to return it to its original state. If symptoms of localized granulation tissue occur after the healing of a wheal that interferes with your life and continues unabated, prompt medical attention is required.