Dilatation of the lower and middle esophagus means that the diameter of the lower and middle esophagus exceeds the normal reference range. Dilatation of the lumen of the lower and middle esophagus may be congenital or acquired, such as congenital dilatation of the esophagus due to the looseness of the esophageal muscularis propria, which may be related to genetic predisposition. If it is caused by acquired causes, it is commonly seen in inflammation, polyps, esophageal cancer, pancreatic achalasia, and other conditions. Dilatation of the lower and middle esophageal lumen usually leads to symptoms such as difficulty in swallowing, choking sensation, and indigestion. It is recommended to consult a doctor to identify the cause of the disease and to treat it with appropriate treatment.