White patches on the back of the hands may be caused by vitiligo, post-inflammatory hypopigmentation, anemic nevi and other diseases. 1. Vitiligo: Vitiligo is a disease in which the destruction of melanocytes leads to white patches on the skin, manifested as white patches on the skin, which can occur in any part of the body. 2. Post-inflammatory hypopigmentation: Post-inflammatory hypopigmentation is a melanin deficiency caused by inflammation. If the back of the hand has been traumatized or eczema and other diseases, the back of the hand will grow white spots after the inflammation subsides. 3. Anemic nevus: Anemic nevus manifests itself as a pale spot on the skin, which can occur on the back of the hand. There are many reasons for white spots on the back of the hands, so it is recommended to consult a doctor for a clear diagnosis.