The early clinical manifestations of lumbar spinal canal tumor and lumbar spine pain are similar, and many patients often delay early diagnosis due to their own negligence or due to incomplete examination by doctors at the time of consultation, which may lead to misdiagnosis. Lumbar spine pain is often caused by lumbar spine diseases such as lumbar disc herniation, lumbar muscle strain and spinal stenosis, with lumbar disc herniation being the most common in clinical practice. In contrast, the early symptoms of lumbar intradural tumor are often not obvious, often taking lumbar and leg pain as the first symptom, and the corresponding sensory telekinetic disorder of the limbs will appear and worsen with the gradual compression of the spinal cord during the course of the disease, even causing paraplegia or partial paraplegia. How to realize the distinction between lumbar spinal canal tumor and lumbar spine pain? The doctor will have a preliminary impression on the condition through careful history and physical examination. Patients with intravertebral tumor have a slow onset and a short course, and often have severe pain in the lumbar region, which is heavier at night than during the day; lumbar spondylosis often has a developmental process and a longer course, which can also occur under certain triggers with acute aggravation, continuous severe pain in the lumbar region, which cannot be relieved by any position, or numbness of the limbs, aggravation of paralysis, urinary and fecal dysfunction, and in serious cases, paraplegia. 2.According to different clinical manifestations and symptoms, doctors will recommend some examinations, including X-ray, CT and MRI, etc. MRI is a recognized examination method to effectively distinguish intravertebral tumor and lumbar spondylosis. For some free discs that protrude into the spinal canal, the image resembles an intradural tumor, and further MRI is sometimes needed to differentiate them. Detailed history taking, careful physical examination, combined with CT and MRI examination, can achieve early diagnosis, reduce the occurrence of misdiagnosis and missed diagnosis, and take the correct treatment plan in time. This can effectively increase the cure rate and improve the quality of life of patients.