Swelling and pain at the edge of the nostrils is very common in clinical practice, because the subcutaneous tissue of the nasal cavity is particularly small, so once there is an infection, the resulting swelling and pain will be very intense. The most common cause of swelling and pain at the edge of the nostrils is nasal vestibulitis, the nasal vestibule is the front part of the nasal cavity, mainly composed of the skin and hair follicles of the nasal vestibule. You can apply erythromycin ointment or sulfur cream locally to treat it, and you can also do microwave or infrared physical therapy to reduce the pain. In addition, it is also necessary to pay attention to regular life, regular diet, eat more vegetables and fruit foods, eat E or D vitamins, reduce the inflammatory reaction. Usual prevention can use warm water to wash the face, in washing the face at the same time for nasal vestibule cleaning, you can prevent the occurrence of nasal vestibulitis.