After tetanus injection, if the vaccine is in the immunization period, there is usually no infection, but if the immunization period is exceeded, there may be a risk of infection. Tetanus vaccination can be categorized into active and passive immunization. The former refers to the active vaccination in which the tetanus toxoid antigen is injected into the body so that antibodies are formed, thus achieving immunity; the latter refers to the post-injury tetanus antitoxin serum vaccination which is not carried out for the whole period of the tetanus active immunization but is carried out after the injury due to improper wound cleaning or more serious trauma. After the completion of active immunization against tetanus, the immunity period is relatively long and lasts for about 10 years. After passive immunization against tetanus, the period of validity is relatively short, effective for about 7-10 days. If an injury occurs after the tetanus immunization period has been exceeded, a second vaccination should be given to avoid infection by Clostridium tetani. After tetanus vaccination, attention should be paid to wound cleanliness and hygiene, and timely disinfection and dressing change to prevent other bacterial infections and inflammation.