Many colorectal tumor patients ask me one question impatiently after surgery: What is the result of my pathology? Has it metastasized and spread? Early or late stage? How long can I live? Do I need chemotherapy? How long will chemotherapy last? I am afraid that these are the most important concerns of patients. In fact, these questions are also of great concern to our doctors! Obviously, the prognosis of a patient is directly related to the pathological stage of his tumor. The postoperative pathology report can tell me and the patient the detailed stage of the tumor. Colorectal cancer can be divided into TNM stages 1, 2, 3 and 4 according to the early and late stages of the disease, and the five-year survival rate of stage 1 patients is often over 90%, and decreases thereafter. Patients with stage I colon cancer do not need chemotherapy, while stage II patients decide whether they need chemotherapy according to the presence or absence of pathological high-risk factors, including: vascular cancer embolism, poor differentiation of tumor, perforation, tumor penetration of plasma membrane, etc. Patients with stage III and stage IV colon cancer often need postoperative chemotherapy due to lymphatic metastasis or distant organ metastasis, and the duration of chemotherapy is about six months. The standard of chemotherapy for rectal cancer is more stringent. It is generally believed that postoperative adjuvant chemotherapy is needed when the tumor penetrates the whole intestinal wall, regardless of whether there are lymph node metastases or not. I believe that most colorectal cancer patients’ tumors can be cured if they follow the treatment plan of their doctors. Here is just a basic knowledge of post-operative chemotherapy, but each patient should decide whether to have chemotherapy or not according to his condition. It is not possible to make a generalization.